Has anyone ever been cured of hemophilia or the genetic abnormality that causes it?
Also, has a hemophiliac or someone who carries the gene ever had a child that wasn’t a hemophiliac AND didn’t carry the gene?
Technically, hemophilia can be cured through a liver transplant, but the risks involved in the surgery and the requirement for lifelong medications to prevent rejection of the new liver may outweigh the benefits – which is why it’s never done.
If you so happen to be a hemophiliac and need a liver transplant then that’s the only way it would happen.
Doctors/medics/researchers are aware, which is why research is done in this area, but not to that extreme… for example, transplanting liver cells, although THIS is still only in research phase.
————
As for your second question.
If an affected male has hemophilia, he WON’T pass it to his son, but will pass the gene to his daughter. (I can’t say that I’ve ever heard of an affected male not passing the gene to his daughter.)
And as for a woman who carries the gene, she has a 50% chance of passing it to her children.
March 7th, 2013 at 1:29 am
Technically, hemophilia can be cured through a liver transplant, but the risks involved in the surgery and the requirement for lifelong medications to prevent rejection of the new liver may outweigh the benefits – which is why it’s never done.
If you so happen to be a hemophiliac and need a liver transplant then that’s the only way it would happen.
Doctors/medics/researchers are aware, which is why research is done in this area, but not to that extreme… for example, transplanting liver cells, although THIS is still only in research phase.
————
As for your second question.
If an affected male has hemophilia, he WON’T pass it to his son, but will pass the gene to his daughter. (I can’t say that I’ve ever heard of an affected male not passing the gene to his daughter.)
And as for a woman who carries the gene, she has a 50% chance of passing it to her children.
References :
My son has Severe Hemophilia A.
Numerous articles, speaking engagements.
You can watch the documentary Bad Blood (on Netflix) and hear from one of the men who was cured through a liver transplant – that he needed.
http://www.youtube.com/watch?v=eU_wobgsXvE
March 7th, 2013 at 1:46 am
I am not aware of anyone that has been cured of hemophilia and I don’t think anyone can be cured of it. Yes it is possible for a hemophiliac to produce a child that is not hemophiliac nor a carrier, it has to be a male that is born like this. This is because if the father is hemophiliac and the mother is perfectly normal or a carrier, one of the male is going to be perfectly fine. This is true because we know that a male can not be a carrier on the Y chromosome and female can carry. Remember: Hemophiliac is a recessive sex linked trait. So it is ONLY possible if the father is hemophiliac and doesn’t matter is the mother is carrier or normal. Only a boy child will be born with such advantage. In biological terms: Father has to be affected and the mother can be homozygous or heterozygous =) Your welcome.
References :
Grade 11 Bio class =)